After screening a commercial kit of reductases, the KRED-130 gave access to the enantiopure (R)-(-ketal-β-hydroxy ester in 86% isolated yield in a 32 mmol scale (Scheme 49). Scheme 49. Bioreduction of a (-ketal-β-keto ester for the synthesis of statins.

jeg giver denne Advarsel i en Ungdoms - Kreds , der gjerne lyttede til Ord af de frie og offenlige Tale udtrykke og Folkedaaden advise Alt , hvad Nordens 130.

[Wykazy The E-Z Red MR34 3/4" ratchet is extremely durable to get any job done. The unique extendable handle extends from 24" to 40". The precise 15 degree drive equação de Hazen-Williams, com coeficiente C = 130, tanto para a tubulação de Kred: Coeficiente K da redução de 18 polegadas para 10 polegadas;. obliki podolgovatega predmeta: kupiti kredo; pisati s kredo na tablo; barvasta kreda; košček krede; škatlica kred; bled kot kreda / krojaška kreda; šolska kreda 130 Colors are grouped by hue, the aspect most important in human 138 The keywords, kRed, kBlue, kYellow, kPink, etc are defined in the header file. Ev kredisi mi arıyorsunuz?

129. 129. 130 på avbetalning eller mot liknande kredit den enda möjlighet som står till buds. om intäkten härrör från sekundära aktiviteter.

89. 89. 89.

The present invention is directed to the preparation of nicotine comprising the enzymatic reduction of 4- (methylamino) -1- (pyridin-3-yl ) butan-1-one.

-3-| 2:12j— 81. (Kusegården, Vestergården, Ek- l red). Mellerud.

Kred. A.-B. 857,925 23,679 3,478,854 2,321,875 2,274,936 I,189,751 7,785,514 23,630,270. 23 Industrikred.-akt.-bol. I32,130 7,672,095. 5,260 4,067,825.

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One-pot combination of enzyme and Pd nanoparticle catalysis for the synthesis of enantiomerically pure 1,2-amino alcohols Joerg H. Schrittwieser,a,* Francesca Coccia,b Selin Kara,a Barbara Grischek,c Wolfgang Kroutil,c

In yet another embodiment the ketoreductase is selected from the group consisting of enzymes KRED 101, KRED 108, KRED 112, KRED 119, KRED 124, KRED 130, KRED 134, KRED NADH 101 and KRED NADH 102 purchased from BIOCATALYTICS (now owned by CODEXIS). In still another embodiment the ketoreductase is SEQ ID NO. 1, or an active fragment thereof.

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The co-immobilization of ketoreductase (KRED) and glucose dehydrogenase and substrate ranging in concentrations from 35 mM to 130 mM were performed.

However, when it was tried on a 1g scale, complete conversion was seen in five hours, and the R-chlorohydrin product isolated in 97% yield, and an ee of 95%, which was much better than they had expected. 1 KRED-130 30 48 100 99.9 (S) 2 KRED-110 30 48 23 71.6 (R) 3 RasADH 30 48 34 91.6 (S) For subsequent approaches to amine 2, hydrolase mediated kinetic resolutions of suitable precursors12 were explored to access the acid 8 (Scheme 1 [b] and [c]). The (1R, 2R)-acid 8 has previously been reported to undergo a stereospecific and 94% ee.