Perfluorooctanesulfonate (PFOS) Perturbs Male Rat Sertoli Cell Blood-Testis Barrier Function by Affecting F-Actin Organization via p-FAK-Tyr(407): An in Vitro Study

Perfluorooctanesulfonate (PFOS) Perturbs Male Rat Sertoli Cell Blood-Testis Barrier Function by Affecting F-Actin Organization via p-FAK-Tyr 407: An in Vitro Study Hin-Ting Wan , Hin-Ting Wan

AU - Thibodeaux, Julie R. AU - Eastvold, Mary L. AU - Ehresman, David J. AU - Bjork, James A. AU - Froehlich, John W. AU - Lau, Christopher. AU - Singh, Ravinder J. AU - Wallace, Kendall B Perfluoroalkyl substances (PFASs) are widely-utilized synthetic chemicals commonly found in industrial and consumer products. Previous studies have examined associations between PFASs and renal function, yet the results are mixed. Moreover, evidence on the associations of isomers of PFASs with renal function in population from high polluted areas is scant. To help to address this data gap, we Chang S, Thibodeaux J, Eastvold M, Ehresman D, Bjork J, Froehlich J, Lau C, Singh R, Wallace K and Butenhoff J (2008) Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS), Toxicology, 10.1016/j.tox.2007.10.014, 243:3, (330-339), Online publication date: 1-Jan-2008.

vitamins, minerals, amino acids, It is primarily perfluorooctane sulfonate (PFOS) and derogations in the case of functional testing of fire-fighting equipment in permanent. lobster (Nephrops norvegicus) in Division 3.a, Functional units 3 and Johansson J. Undeman E. (2020) Perfluorooctane sulfonate (PFOS) av S Polo Ruiz de Arechavaleta · 2018 — PFOS (perfluorooctane sulfonate) and PFOA (perfluorooctanoic acid) are the based on a mathematical function that aims to relate intensity of the rain with the. av F från Vätternvårdsförbundet · 2015 — EFSA (2008) Perfluorooctane sulfonate (PFOS), perfluorooctanoic acid S. (2011) Prenatal Exposure to PFOS or PFOA Alters Motor Function in Mice in a. mixture components showed differences depending on chain length and functional group. sulfonate, perfluorooctanoic acid, and perfluorooctane sulfonate.

The resistance of PFOA and PFOS to environmental degradation, their bio-accumulation in food chains, and their long In situ perfluorooctane sulfonate sediment-water distribution factor (KD) values, bioaccumulation factor (BAF) values, and biota-sediment accumulation factor (BSAF) values showed a remarkable agreement among reference and impacted sites, 10 weeks after the incident as well as after 3 years.

Perfluorooctanesulfonate (PFOS) is a compound of global concern because of its persistence and bioaccumulation in the environment. Nevertheless, little is known of the potential for PFOS biodegradation, even though the importance of characterizing the function and activity of microbial populations detected in the environment has been discussed.

Description Chang S, Thibodeaux J, Eastvold M, Ehresman D, Bjork J, Froehlich J, Lau C, Singh R, Wallace K and Butenhoff J (2008) Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS), Toxicology, 10.1016/j.tox.2007.10.014, 243:3, (330-339), Online publication date: 1-Jan-2008. PDF | PFOS (perfluorooctanesulfonate, or perfluorooctane sulfonic acid) is an anthropogenic fluorosurfactant widely used in consumer products. While its | Find, read and cite all the research INTRODUCTION Perfluorooctanesulfonate (PFOS) is widely distributed and persistent in humans and wildlife.

Perfluorooctane sulfonate Fluoro-organic chemicals such as perfluoro-octane sulfonate (C8F17SO3H)(PFOS), have been used since the 1950s in soil- and

Serum perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) concentrations and liver function biomarkers in a population with elevated PFOA exposure Environ Health Perspect . 2012 May;120(5):655-60. doi: 10.1289/ehp.1104436. Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoic Acid (PFOA) November 2017 . Introduction This fact sheet, developed by the U.S. Environmental Protection Agency (EPA) Federal Facilities Restoration and Reuse Office (FFRRO), provides a summary of two contaminants of emerging concern, perfluorooctane Perfluorooctane sulfonate mediates microglial activation and secretion of TNF-α through Ca2+-dependent PKC-NF-кB signaling. Int. Immunopharmacol. 28 , 52–60 (2015).

Know the exact difference between the two in a table format with Examples. Software Testing Help Know the Difference Between Functional Testing Vs Non-Functional BackgroundPerfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) These alterations in hepatic metabolism and function have been attributed to Information about Perfluorooctane Sulfonate (PFOS), Its Salts and Its Precursors. a function or functions dependent in whole or in part on its shape or design, PFOS (perfluorooctanesulfonate, or perfluorooctane sulfonic acid) is an PFOS exerts its disruptive effects on Sertoli cell function downstream through Akt1/2. August 2020. Role of CYP2B6 in Perfluorooctanesulfonic Acid (PFOS)-Induced.
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The decision followed the announcement by a major US manufacturer (3M) to globally phase out 2007-10-26 · Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS). Shu-Ching Chang Medical Department, 3M Company, St. Paul, MN 55144, United States. PFOS (perfluorooctanesulfonate, or perfluorooctane sulfonic acid) is an anthropogenic fluorosurfactant widely used in consumer products. While its use in Europe, Canada and the U.S. has been banned due to its human toxicity, it continues to be used in China and other developing countries as a global pollutant.

Corrigendum to "Renal function and isomers of perfluorooctanoate (PFOA) and perfluorooctanesulfonate (PFOS): Isomers of C8 health project in China" [Chemosphere 218 (2019) 1042-1049] Chemosphere . 2019 Apr;220:1208. doi: 10.1016/j.chemosphere.2019.01.051.
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Erratum: Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury In the Results section, under the sub-heading ‘PFOS perturbs Sertoli cell TJ-barrier function through changes in

Dietary treatment of male C57BL/6 mice with 0.002% (w/w) PFOAor 0.005% (w/w) PFOS for 10 days resulted in significant reductions in serum levels of cholesteroland triglycerides, a moderate increase in the serum activity of alkaline phosphatase (ALP) and hepatomegaly, without affecting other immune organs. perfluorooctanesulfonate.

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Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant (POP) and emergent contaminant that are widespread in the environment. Understanding the mechanisms controlling the distribution of PFOS and its isomers between hydrargillite and the water phase is important in order to study their redistribution and mobility in the environment.

In this study, adult male C57BL/6 mice were given by gavage 0, 5, 20 or 40 Available online at www.sciencedirect.com Toxicology 243 (2008) 330–339 Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS)夽 Shu-Ching Chang a , Julie R. Thibodeaux b,1 , Mary L. Eastvold c , David J. Ehresman a , James A. Bjork d , John W. Froehlich e,2 , Christopher Lau b , Ravinder J. Singh c , Kendall B. Wallace d , John L 2 . Technical Fact Sheet – PFOS and PFOA PFOS and PFOA can also be formed by environmental degradation or by metabolism in larger organisms from a large group of related Perfluorooctanesulfonate (PFOS) is widely distributed and persistent in humans and wildlife. Prior toxicological studies have reported decreased total and free thyroid hormones in serum without a major compensatory rise in thyrotropin (TSH) or altered thyroid gland histology. 2021-04-19 · In 2000 several member countries agreed to informally work together to collect information on the environmental and human health hazards of perfluorooctane sulfonate (PFOS) to produce a hazard assessment. The decision followed the announcement by a major US manufacturer (3M) to globally phase out 2007-10-26 · Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS). Shu-Ching Chang Medical Department, 3M Company, St. Paul, MN 55144, United States. PFOS (perfluorooctanesulfonate, or perfluorooctane sulfonic acid) is an anthropogenic fluorosurfactant widely used in consumer products.